Polynucleotides FAQs

How do polynucleotides work?

Polynucleotides are an injectable, skin-boosting, regenerative treatment that has gained popularity in recent years. Although, they have been used in medicine since the 1980’s to treat joint issues.

Polynucleotides are made up of chains of nucleotides, which are the building blocks of DNA and RNA. When used in aesthetics, polynucleotides are typically derived from the sperm of salmon or trout, & are then purified & sterilised for medical use. They are then injected into the skin to provide instant hydration & long term bio-remodelling.

How long does it take to see a difference with polynucleotides?

Most notice a difference after 2-4 weeks, but your skin will continue to improve with optimum results expected about 3 months after the course of treatment has been completed. The recommended course of polynucleotides is 3 treatments taken 3-4 weeks apart. One treatment every 6 months is recommended to maintain your results.

What are the benefits to polynucleotides?

Polynucleotides have several skin-boosting benefits for the skin, including improving skin texture & elasticity & reducing fine lines and wrinkles. They do this by providing instant hydration whilst also promoting fibroblast proliferation & collagen synthesis. They are also thought to have anti-inflammatory & wound-healing properties, which can help to reduce redness, swelling, & other signs of skin damage.

Like hyaluronic acid skin boosters, polynucleotides create dewy looking skin, adding a soft volume & hydration effect. In addition to this, polynucleotides work to boost fibroblast production, inducing tissue repair processes, reducing inflammatory processes, regulating melanogenesis & promoting hydration in the skin. Polynucleotides stimulate regeneration of the skin at the cellular level so it takes time to be seen visually in terms of improved texture, minimised pores & pigmentation.

Depending on the degree of ageing your skin has & your ability to create quality tissue when stimulated, your diet & lifestyle, your skin quality will improve gradually as the tissues regenerate following treatment.

How do I prepare for Polynucleotide treatment?

As with any other injectable treatment, unless prescribed, avoid Ibuprofen/aspirin, exercise and alcohol 24 hours prior to your treatment. Ensure you’ve had a drink and something to eat and remove any makeup. Under eye bags can look worse before they improve.

What happens during the treatment?

Depending on the area being treated a numbing agent will be applied for your comfort. In a sterile fashion, the polynucleotide is injected using either needle or cannula to deposit the polynucleotide. The process will take approximately 10 minutes, however plenty of time is given to take the procedure at your pace.

What are the side effects & risks of polynucleotide treatments?

Side effects and complications include but are not limited to:

Pain or stinging whilst the injection is performed.
Localised swelling, redness and or tenderness.
Bleeding at the sites of injection.
Bruising

Rare Side Effects

Persistent or prolonged pain, swelling, or inflammation.
Infection (can occur within days or as long as months).
Allergy
Compression / Vascular Compromise